Earth's climate is changing. Reliable climate predictions are essential for developing climate change mitigation and adaptation strategies, and thus have a significant socio-economic value. However, climate predictions are still highly uncertain due largely to our limited understanding of the role of clouds in climate change. The challenge in understanding clouds' role in climate change stems mostly from a scale separation between the cloud or cloud field scale (102 - 104 m) to the global climate scale (>106 m). Despite this scale separation, clouds and the climate system are strongly coupled. Accounting for this large range of scales in a single research framework is considered the "holy grail" of our research field. My main research goal is to develop innovative setups that account simultaneously for cloud scale processes and for changes in the large-scale tropical circulation. Using these setups, I will examine the cloudresponse to anthropogenic perturbations and specifically the co-variability, compensations and interactions between different cloud regimes, which are connected by the large-scale atmospheric circulation. My aim is to connect local cloud/cloud field scale anthropogenically driven perturbations to the larger climate scale.